Betty never misses an episode of her favorite soap opera, "A reason to love." After a mind-altering run-in with two hit-men while watching an episode, Betty transforms into "Nurse Betty" and embarks on a mission to find her one true love, Dr. David Ravell.

Frank Castle is a man who has seen too much death. Undercover and on his final assignment, Frank plays his role perfectly, but the operation gets out of control and a young man named Bobby Saint is inadvertently killed. Howard Saint holds Castle responsible for the death of his son and risks his newfound legitimacy on a wholesale mission of blood-vengeance. Saint and his lieutenants butcher Frank's family during a family reunion and leaves Frank for...